Liberon is an auxiliary food source of alkaloids (harmine, harmaline, harmolole), flavonoids (chrysin, puerarine, daidzin, daidzein) and other biologically active substances, contained in the extracts of Passiflora incrarnata and Kudzu medicinal plants. The action of all Liberon ingredients is clinically confirmed.
The main active components that determin the biological effects of Passiflora incarnate are alkaloids (harmine, harmaline, harmolole), which repress monoamine oxidase ferment, stipulating the serotonin, noradrenaline and dophamine concentration in the synaptic cleft, and the amelioration of mediators transportation between neuron terminals (nerve cells). In this way Passiflora incarnata extract exhibits marked antidepressive properties. The most active flavonoid of Passiflora incarnate is chrysin, which is a partial agonist of benzodiazepine receptors, has a sedative (calming), anxiolytic and gentle drowsy effect. The methanolic extract of Passiflora incarnate has a peripheral and central restorative antinociceptive activity, intermediated by the GABA modulation and the opiate receptors. The use of Passoflora incarnate flowers extract significantly reduces the manifestations when withdrawing benzodiazepines, alcohol, morphine, nicotine and marihuana (Dhawan K., 2001, 2002, 2003, 2004). The effect of Passiflora incarnate is analogous to the effect of disulphiram for dopamine beta-hydroxylase (DBH) ferment inhibition, as a result the level of neural dopamine increases, which may have a significant impact on the behavior modification, concerning the search for drugs.
Kudzu extract (Pueraria montana var. lobata)
Kudzu (Pueraria montana var. lobata) is classified among the 50 most important plants of the traditional Chinese medicine. It has been used thousands years for control of alcohol withdrawal syndrome and intoxication treatment. The studies undertaken highlight that at least one of the plant’s extract main isoflavones, daidzin, is able to change the central serotonergic and catecholaminergic transmitters, which are important for alcohol effects realization ((Gao et al., 2001; Keung, 2003; Rooke et al., 2000). Moreover, in virtue of mitochondrial ALDH2 inhibition, daidzin blocks the metabolic route of serotonin to the 5-hydroxyindole acetic acid (5-HIAA) and dophamine to 3,4 dihydroxyphenylacetic acid (DOPAC), contributing to the normalization of neurotransmitters data level in the brain synapse. Puerarine, one of the most known isoflavones found in Kudzu root extract, is a vasodilating agent and is approved for such a usage in China in case of heart or brain attack (Wu et al., 2014).
The studies, undertaken by Gilead Sciences Inc., have shown the opportunity to use Kudzu extract for cocaine addiction treatment.
Kudzu (Pueraria montana var. lobata) and Passiflora incarnate extracts, which can be found in Liberon, are used for active prevention and combined therapy of:
- neuropathic pain
- sustainable stress conditions, increased psychoemotional pressure
- metabolic disturbance and adaptation of organism to adverse factors of environment
- anxious feeling reduction
- as a supplementary tool in combined therapy of addictive conditions.
People with systematic chronic diseases must consult the docor in charge before taking Liberon.
Liberon is bolted by mouth, washed down with water, 1-2 capsules three times a day one hour before or one hour after meals. The dose can be significantly increased in case the doctor in charge gives corresponding recommendations.
Well-tolerated and has a high margin of safety. Not recommended for use in gestation or nursing period.
Allergic reactions on separate components of Liberon.
If taking Liberon in big quantities unnecessarily, dyspeptic phenomena may appear (nausea, vomiting, diarrhea), apathy, drowsiness. Symptomatic treatment, gastric lavage and enterosorbents administration recommended.
Recommended to be taken with diligence with anti-coagulants due to the blood clotting time increase under the action of Passiflora incarnata. During administration, it is necessary to avoid taking alcohol or narcotic substances.
Store in original package, in a cool, dry, light-proof place, at a temperature from 18 °С to 25 °С and a relative humidity not exceeding 75%.
Keep out of reach of children!
Conclusion by state sanitary-epidemiological expertise № 05.03.02-04/60741 from 19.06.2012.
“Liberon” medical center
In “Liberon” medical center, we use a unique drugs, alcohol and gambling addiction healing method, that has no counterparts. The method involves the use of neuroleptics, analgesics and multicomponent medications of vegetable origin. The original technique is conducted on the ground of infusional and hepatoprotective therapy, it is also accompanied with somatic disorders adjustment and individual behavioral therapy sessions from the first day of center stay.